Mark Canciani’s PhD defense

Title: “Biological altruism, eusociality and the superorganism: a critical analysis of the role of biological altruism within eusociality research”

Time: 12/03/2020, 11:00

Place: Sala de Grados, Facultad de Educación, Filosofía y Antropología

IAS-Talk by Çağlar Karaca (Kastamonu University): “Relational Basis of the Organism’s Self-organization”

Relational Basis of the Organism’s Self-organization

Çağlar Karaca 

Thursday 5 March at 11:15 Centro Carlos Santamaria (B14)

Abstract:

In this thesis, I discuss the organism’s self-organization from the perspective of relational ontology. I critically examine scientific and philosophical sources that appeal to the concept of self-organization. By doing this, I aim to carry out a thorough investigation into the underlying reasons of emergent order within the ontogeny of the organism. Moreover, I focus on the relation between universal dynamics of organization and the organization of living systems. I provide a historical review of the development of modern ideas related to self-organization. These ideas have been developed in relation to various research areas including thermodynamics, molecular biology, developmental biology, systems theory, and so on. In order to develop a systematic understanding of the concept, I propose a conceptual distinction between transitional self-organization and regulative self-organization. The former refers to the spontaneous emergence of order, whereas the latter refers to the self-maintaining characteristic of the living systems. I show the relation between these two types of organization within biological processes. I offer a critical analysis of various theories within the organizational approach. Several ideas and notions in these theories originate from the early studies in cybernetics. More recently, autopoiesis and the theory of biological autonomy asserted certain claims that were critical toward the ideas related to self-organization. I advocate a general theory of self-organization against these criticisms. I also examine the hierarchical nature of the organism’s organization, as this is essential to understand regulative self-organization. I consider the reciprocal relation between bottom-up and top-down dynamics of organization as the basis of the organism’s individuation. To prove this idea, I appeal to biological research on molecular self-assembly, pattern formation (including reaction-diffusion systems), and the self-organized characteristic of the immune system. Finally, I promote the idea of diachronic emergence by drawing support from biological self-organization. I discuss the ideas related to constraints, potentiality, and dynamic form in an attempt to reveal the emergent nature of the organism. To demonstrate the dynamicity of form, I examine research into biological oscillators. I draw the following conclusions: synchronic condition of the organism is irreducibly processual and relational, and this is the basis of the organism’s potentiality for various organizational states.

IAS-Research Seminar by Enara García and Iñigo Arandia-Romero (UPV/EHU): “La patología en la filosofía de la individuación de Gilbert Simondon”

La patología en la filosofía de la individuación de Gilbert Simondon

Enara García and Iñigo Arandia-Romero (UPV/EHU)

Tuesday 19 November 2019 at 11:30  (Centro Carlos Santamaria, B14)

Language: Spanish

Abstract

En este trabajo, proponemos mirar en la filosofía de la individuación de Gilbert Simondon para ofrecer un entendimiento de lo patológico desde una ontología procesual y relacional que diluye tanto la discontinuidad entre procesos vitales y psíquicos como la dicotomía entre individuo y sociedad. Simondon propone estudiar, no tanto los individuos ya constituidos, sino el proceso de ontogénesis del individuo que, en el caso del ser humano, está mediado por su participación en lo colectivo. En este proceso, la afectividad juega un papel central, ya que atraviesa tanto la individuación vital, como la psíquica y la colectiva, conectando el conjunto de tensiones y potencialidades existentes previas al proceso de individuación (lo pre-individual) con el individuo constituido. Este cambio de perspectiva permite entender la patología, no en términos normativos, sino como el estudio de la dinámica de la afección, con su historia previa y sus posibilidades de evolución, e influyendo también en nuestra comprensión de los procesos terapéuticos.

IAS-Research Seminar by Manuel Heras-Escribano and Miguel Aguilera (UPV/EHU): “Autopoiesis in the Game of Life”

Autopoiesis in the Game of Life

Manuel Heras-Escribano and Miguel Aguilera (UPV/EHU)

Tuesday 3 December 2019 at 11:30  (Centro Carlos Santamaria, B14)

Abstract

In this talk, we will review a series of papers by Randall Beer. In these work he uses the Game of Life to exemplify different aspects and concepts autopoiesis and enactivism, using the model as a laboratory in which theoretical concepts can be developed to the point where they can be used to actually calculate things (autopoietic networks and operational closure, destructive/non-destructive perturbations, structural coupling…). Reviewing the work in this minimal world we will discuss 1) how different aspects of autopoiesis and autonomy can or cannot be displayed by minimal agents in a cellular automata, 2) how this type of study may be useful for concretizing ongoing debates on the foundations of enaction.

IAS-Research Seminar by Iñigo Arandia-Romero (UPV/EHU): “Enactive and Simondonian reflections on placebo phenomena”

Enactive and Simondonian reflections on placebo phenomena

Iñigo Arandia-Romero (UPV/EHU)

Tuesday 21 January 2019 at 11:30  (Centro Carlos Santamaria, B14)

Abstract

Placebo effects have played a key role in the history of medicine, and they are still nowadays extremely useful as the gold standard to test the efficacy of many treatments through Randomized Control Trials (RCT). Despite its importance, they did not receive much research attention until the last two decades or so, and we are still far from a complete understanding of the phenomena related to the umbrella-term placebo. We will show that part of the problems and limitations to understand the placebo effects is related to theoretical assumptions that are often implicit in the current biomedical paradigm: the mind-body dualism, the predominance of individualism, the reductionist tendency to study isolated factors, and neglecting the dynamic nature of human beings (i.e, their history and evolution process). By taking advantage of the distinction between pre-reflective and reflective consciousness employed in the phenomenological tradition, the theoretical framework of the enactive perspective, and the philosophy of individuation developed by Gilbert Simondon, we will propose a novel way to analyze placebo interventions that overcomes some of the limitations of current approaches, and is able to explain part of the huge variability of placebo responses, across subjects and across conditions. Instead of offering a full account of placebo phenomena, we will provide insights to better analyze different experimental paradigms employed in placebo research considering that each subject is an embodied agent situated in a social environment with concrete problems that can be interpreted as a sense-making challenge or a search for meaning. Then, the placebo intervention can be understood as just the last step that triggers a large response but that would be impossible without the history of the subject, all her previous attempts to cope with her condition in her social context, the patient-practitioner interaction and other features that are often neglected or labelled as non-specific in the placebo literature.

IAS-Research Seminar by Arantza Etxeberria (UPV/EHU): “Revisiting the “organism/environment interaction” category”

Revisiting the “organism/environment interaction” category

Arantza Etxeberria (UPV/EHU)

Tuesday 12 November 2019 at 11:30  (Centro Carlos Santamaria, B14)

Abstract

The “organism/environment interaction” has been an important category in biomedical sciences since the end of the 19th century. It brings forward the view of the organism as an autonomous biological entity, with an internally controlled and regulated physiology, interacting with an environment providing opportunities and viability constraints for its living activities. It is often remarked that organisms can transform or construct these environments according to their needs (dialectical views of development and evolution; niche construction; technologies), or that they need to accommodate their lives and norms to restricted environments in case of disease. This presentation will introduce work in progress intending to examine and discuss the current scientific role of this category in biomedicine. On the grounds of some conceptual and empirical challenges, proposals tending to privilege deeper interconnectivities will be considered. This research is integrated within the Inter-identity Project (Mineco FFI2014-52173-P Research Project on Identities in interaction).

IAS-Research Seminar by Guglielmo Militello: Motility Control of Symbionts and Organelles by the Eukaryotic Cell

Motility Control of Symbionts and Organelles by the Eukaryotic Cell

Guglielmo Militello

Tuesday 29 at 11:30 (Centro Carlos Santamaria B14)

 

Motility occupies a decisive role in an organism’s ability to autonomously interact with its environment. However, collective biological organizations exhibit individual parts, which have temporally or definitively lost their motor capacities, but still able to autonomously interact with their host. Indeed, although the flagella of bacterial symbionts of eukaryotic cells are usually inhibited or lost, they autonomously modify the environment provided by their host. Furthermore, the eukaryotic organelles of endosymbiotic origin (i.e., mitochondria and plastids) are no longer able to move autonomously; nonetheless, they make a cytoskeletal-driven motion that allows them to communicate with other eukaryotic cells and to perform a considerable number of physiological functions. The purpose of this article is twofold: first, to investigate how changes in the motile capacities of the parts of a nested biological organization affect their interactive autonomy; second, to examine how the modification of the interactive autonomy of the individual parts influences the constitutive autonomy of the collective association as a whole. The article argues that the emergence and maintenance of collective biological identities involves a strict control of the motile abilities of their constituting members. This entails a restriction, but not necessarily a complete loss, of the agential capacities of the individual parts.

 

IAS-Research talk by Maria Jimena Clavel (University of St. Andrews): “Embodying imagination “

Date and time: July 2, Tuesday, 11:30 a.m.

Location: Carlos Santamaría Building, Room B14.

Speaker: Maria Jimena Clavel (University of St. Andrews)

Title: Embodying imagination

Abstract:

This piece is part of a larger project that aims at showing that imagination is constrained as a consequence of its embodied character and that explores the consequences of that thesis in our engagement with art and in our social interactions. Traditionally, we think of imagination as a paradigmatic case of offline cognition, i.e. cognitive endeavors that do not directly involve real-time adaptive interactions with our surroundings. In this piece we challenge this more traditional understanding of imagination and argue that exercises of imagination are embodied. We examine two embodied approaches to imagination that can be found in the literature: a radical enactive approach (see Hutto 2006, Medina 2013) and a predictive approach to imagination (see Kirchhoff 2017); and what it means for imagination to be embodied from the perspective of these two approaches. From the perspective of the first approach, our imaginative engagements are a re-enactment of our interactions with the environment and are better understood by referring to agent-world dynamics. From the perspective of the second approach, imagination is supported by the same predictive mechanism that supports perception. Here we explore the possibility of a middle ground between these two positions in what concerns imagination, and the notion of embodiment that stems from it. Importantly, one consequence of this approach is that imagination is constrained by its embodied character.

IAS-Research Seminar by Iñigo Arandia. “Epistemic entanglement in the macroscopic world”

Date and time: April 9th, Tuesday, 11:30 a.m.

Location: Carlos Santamaría Building, Room B14.

Speaker: Iñigo Arandia (UPV/EHU)

Title: “Epistemic entanglement in the macroscopic world”

Abstract

Scientific non-reductionism emphasizes that the whole is more than the sum of the parts. Beyond metaphor, such holistic idea can be made concrete (namely, mathematically formulated and empirically testable) via the notion of entanglement, which is a foundational concept and an established phenomenon in quantum mechanics related to Heisenberg’s uncertainty principle (a fundamental limit to the precision of simultaneously measuring two complementary variables, like the position and momentum of an electron, which is not a consequence of experimental limitations). Here we present a classical analog of entanglement, where uncertainty relations arise from experimental commitments, like the selection of variables and/or subsystems, or ignorance about the context. Inspired by a theoretical work offering a definition of entanglement in a model of macroscopic brownian particles (Allahverdyan et al., 2005), we propose a general sufficient condition for epistemic entanglement that is valid for any underlying dynamics and any pair of macroscopic stochastic observables. Our bound reflects a trade-off between inter-vs-intra particle correlations, and only requires estimating dispersions. This makes it empirically accessible and also somewhat intuitive. We explored the origin of epistemic entanglement by taking advantage of analytical results available in brownian models and simulations of stochastic systems. Then, we applied our sufficient condition to behavioral data of fly courtship, and found entanglement between position and coarse-grained velocity. This result implies the existence of macroscopic correlations that cannot be effectively explained in causal terms, thus limiting the common cause principle. Our work also challenges the idea of pure objectivity, as our choice of measurement variables induced epistemic correlations that cannot be adjudicated to the observed system but that, through coarse-graining, belong to the observer.

IAS-Research Seminar by Miguel Escribano. “G.W. Leibniz y el problema del origen de los cuerpos orgánicos. Educción y preformacionismo”

Date and time: January 22, Tuesday, 14:30 a.m.

Location: Carlos Santamaría Building, Room B14.

Speaker: Miguel Escribano (UPV/EHU)

Title: “G.W. Leibniz y el problema del origen de los cuerpos orgánicos. Educción y preformacionismo”

Abstract

“El problema del origen de la vida, como hoy en día se plantea, no es directamente abordado durante la modernidad filosófica. Existen, sin embargo, algunos debates que podríamos considerar al respecto por su cercanía a este problema. El caso de G.W. Leibniz es especialmente relevante. Por un lado, su Dinámica tiene la pretensión de convertirse en una ‘ontología general’ que de cuenta de todas las parcelas de lo real en términos de fuerza y forma. En este sentido, su visión de la naturaleza implica una cierta continuidad y coordinación entre las dinámicas características a los tres reinos naturales. Este programa ontológico no está exento de contradicciones. Leibniz nos aporta algunas herramientas para abordar estas contradicciones. En esta presentación haré mención a dos de ellas: por un lado, la teoría de la educción (importancia del pensamiento químico) y, por otro lado, la idea de preformación (importancia del pensamiento biológico). Considerando ambas teorías se plantea el siguiente problema: ¿existe una incompatibilidad entre la perspectiva diacrónico-embriogenética (biológica) que defiende que toda forma orgánica procede de otra forma orgánica y la perspectiva sincrónico-emergente (química) que defiende por su parte que la dinámica organizacional que caracteriza a un organismo educe a un cierto nivel de complejidad natural?”