Fundamentals of IAS-Research Seminars 2018. Seminar 1. The organizational approach to minimal living systems

06/03/2018 @ 15:00 – 17:00
Centro Carlos Santamaría, B14
Fundamentals of IAS-Research Seminars 2018
6 bi-weekly seminars exploring the basic research lines of IAS-Research

Seminar 1 run by: Kepa Ruiz-Mirazo

Keywords: autopoiesis, autonomy, self-organization (in physics/chemistry/biology), minimal function and agency, functional differentiation and integration, metabolism, biological boundaries and individuality, protocells, origins of life, enabling constraints, regulation and hierarchical organization, (open-ended) evolution; H. Maturana & F. Varela, R. Rosen, T. Ganti, S. Kaufmann, H. Morowitz, H. Jonas.


Ruiz-Mirazo, K. and Moreno, A. (2012). Autonomy in evolution. From minimal to complex lifeSynthese, 185(1), 21–52.

Further Readings:

Etxeberria, A. and Umerez, J. (2013). Organization. In Dubitzky, W., Wolkenhauer, O., Cho, K-H. and Yokota, H. (eds.) Encyclopedia of Systems Biology. New York: Springer: 1612–1615.

Karsenti, E. (2008). Self-organization in cell biology: A brief history. Nature Reviews Molecular Cell Biology, 9, 255–262.

Letelier, J. C. et al. (2003). Autopoietic and (M,R) systems. Journal of Theoretical Biology, 222, 261–272.

Mossio, M., Bich, L. and Moreno, A. (2013). Emergence, closure and inter-level causation in biological systems. Erkenntnis, 78(2), 153–178.

Ruiz-Mirazo, K., Peretó, J. and Moreno, A. (2004). A universal definition of life: autonomy and open-ended evolution. Origins of Life and Evolution of Biospheres, 34 (3), 323–346.